In the aftermath of two brutal New York City murders, quadriplegic detective Lincoln Rhyme and his team work doggedly to prevent additional killings by a time-obsessed serial murderer.
Chasing down a serial killer who complicates his crimes by leaving behind evidence implicating innocent people, Lincoln Rhyme and Amelia Sachs reluctantly team up for the investigation only to find themselves rendered the killer's next targets.
When a troubled teenager is pushed over the edge by cyber-bullies, leading to a series of vengeful murders, body-language expert Kathryn Dance and Deputy Michael O'Neil pursue the teenager when he disappears.